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CR medical consultants say that erection problems can be an early warning sign of heart disease, high blood pressure, or diabetes. Structurally vardenafil is similar to sildenafil, while tadalafil is very different. Vardenafil is almost 10 times more biochemically potent than sildenafil, therefore a lower dose is needed to facilitate the penile erection, potentially resulting in less side effects.

Peyronie’s Disease Peyronie’s disease or curvature of the penis is a condition in which scar tissue develops inside the penis. There is no cure for Peyronie’s disease, however, there are medications that can reduce symptoms of the disease. Erectile Dysfunction Erectile dysfunction is the failure to achieve or maintain an erection. Pulmonary Hypertension Pulmonary hypertension is elevated pressure in the pulmonary arteries that carry blood from the lungs to the heart. If the condition goes undiagnosed, more severe symptoms may occur.

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Keep your diabetes under control, and you can lower your risk of sexual and urologic problems. Senior Sex Enjoying a satisfying sex life as we age is important to both physical and mental health. As we age, diseases and conditions may pose challenges in our sexual health, and sexual experiences. Learn how to manage your conditions and still have a gratifying sex life as you age. Men may take it socially with other drugs, rather than for treatment of a medical condition. Night Sweats Night sweats are severe hot flashes that occur at night and result in a drenching sweat.

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Treatment options for multiple sclerosis vary depending on the type and severity of symptoms. Scleroderma Scleroderma is an autoimmune disease of the connective tissue. Treatment of scleroderma is directed toward the individual features that are most troubling to the patient.

Severe Side Effects

The side effects of vardenafil are potentially less than sildenafil , but more data are needed. In a recent study on men with erectile dysfunction and diabetes, vardenafil improved their erectile dysfunction. Common sexual problems in men include erectile dysfunction , premature ejaculation, and loss of libido.

Eating healthy, exercise, managing stress, and knowing when to have medical tests for a particular age is key to disease prevention in men. Sexual Problems in Women Sexual dysfunction refers to a problem that arises during any phase of the sexual response cycle, preventing an individual or couple from experiencing sexual satisfaction. Sex, Urinary, and Bladder Problems of Diabetes Having diabetes can mean early onset and increased severity of bladder symptoms and changes in sexual function. Men may have erectile dysfunction; and women may have problems with sexual response and vaginal lubrication.

As pulmonary hypertension worsens, some people with the condition have difficulty performing any activities that require physical exertion. While there is no cure for pulmonary hypertension, it can be managed and treated with medications and supplemental oxygen to increase blood oxygen levels. Multiple Sclerosis Multiple sclerosis symptoms vary from person to person, and can last for days to months without periods of remission.

  • Counterfeit drugs are illegal and may be harmful to your health.
  • Viagra and alpha-blocker medications can both lower blood pressure, so taking Viagra with alpha-blocker medications can result in low blood pressure.
  • They could have the right active ingredient but at the wrong dose.
  • Clinical data showed that patients taking saquinavir or erythromycin in conjunction with Viagra were found to have significantly increased levels of Viagra’s active ingredient sildenafil in their blood.
  • CYP3A4 is an important enzyme in the body, mainly found in the intestines and liver.
  • It may be contaminated or contain the wrong or no active ingredient.

Selectivity is the ability of the drug to attach to the specific enzyme PDE 5 found in penile tissues. Vardenafil is more selective than sildenafil and tadalafil to PDE5, which again means a lower dose is needed with potentially less side effects. Tadalafil is very specific for PDE5 and is also very specific for the enzyme PDE11. Unfortunately, we don’t know much about PDE11, which is found in the heart, in the pituitary gland in the brain and in the testicles. Pharmacokinetics, half-life, is how long the medication stay s in the blood. Sildenafil has a half-life of 4 hours and vardenafil has a half-life of 4-6 hours while tadalafil has a half-life of 17.5 hours. This means that vardenafil should act longer than sildenafil but the clinical significance is not known.